Publications

Publications arising from collections funded by ABN-Oncology

  1. Creaney J, Dick IM, Segal A, Musk AW, Robinson BW. Pleural effusion hyaluronic acid as a prognostic marker in pleural malignant mesothelioma. Lung Cancer 2013; 82: 491-498
  2. Creaney J, Sneddon S, Dick IM, Dare H, Boudville N, Musk AW, Skates S, Robinson BWS. Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions And Serum. Disease Markers 2013; 35: 119-127

  3. Varano della Vergiliana JF, Lansley S, Porcel JM, Martn SB, Creaney J, Waterer G, Temple S, Lee YCG.  Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells. PLOSone 2013 8(5): e63873

  4. Cadby G, Mukherjee S, Musk AW, Reid A, Garlepp M, Dick I, Robinson C, Hui J, Fiorito G, Guarrera S, Beilby J, Melton PE, Moses EK, Ugolini D, Mirabelli D, Bonassi S, Magnani C, Dianzani I, Matullo G, Robinson B, Creaney J, Palmer LJ. A genome-wide association study for malignant mesothelioma risk. Lung Cancer 2013; 82: 1-8

  5. Matullo G, Guarrera S, Betti M, Fiorito G, Ferrante D, Voglino F, Cadby G, Di Gaetano C, Rosa F, Russo A, Hirvonen A, Casalone E, Tunesi S, Padoan M, Giordano M, Aspesi A, Casadio C, Ardissone F, Ruffini E, Betta PG, Libener R, Guaschino R, Piccolini E, Neri M, Musk AW, de Klerk NH, Hui J, Beilby J, James AL, Creaney J, Robinson BW, Mukherjee S, Palmer LJ, Mirabelli D, Ugolini D, Bonassi S, Magnani C, Dianzani I.  Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. PLoS One. 2013 8(4):e61253.

  6. Schwed-Lustgarten DE, Deshpande C, Aggarwal C, Wang C-L, Saloura V, Vachani A, Wang LP, Litzky L, Feldman M, Creaney J, Nowak A, Langer C, Inghilleri S, Stella G, Albelda SM.   Thymidylate Synthase and Folyl-polyglutamate synthase (FPGS) are not clinically useful markers of response to pemetrexed [Pem] in patients with malignant pleural mesothelioma [MPM].  J Thorac Oncol.  2013 8: 469–477

  7. Creaney J, Dick IM, Dare H, deMelker Y, Nowak AK, Musk AW, Robinson BWS. Does CA125 binding to mesothelin impact the detection of malignant mesothelioma. Lung Cancer 2013 80:39-44

  8. McIver SC, Loveland KL, Roman SD, Nixon B, Kitazawa R, McLaughlin EA. The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis. Andrology. 2013, 1, 517-529

  9. Lau LMS, Dagg RA, Henson JD, Au AYM, Royds JA, Reddel RR. Detection of alternative lengthening of telomeres by telomere quantitative PCR. Nucleic Acids Research. 2013; 41:2

  10. Whittier KL, Boese EA, Gibson-Corley KN, Kirby PA, Darbo BW, Qian Q, Ingram WJ, Robertson T, Remke M, Taylor MD, O’Dorisio M. G-protein coupled receptor expression patterns delineate medulloblastoma subgroups.  Acta Neuropathologica Communications. 2013, 1:66

  11. Martin et al., Metformin Accelerates the Growth of BRAFV600E-Driven Melanoma by Upregulating VEGF-A. Cancer Discovery 2012 2:344-355

  12. Dutton-Regester et al., Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma. Pigment Cell Melanoma Res 2013 26:852-60

  13. Tomicic et al., Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs.  Biochim Biophys Acta 2013 1833:1832-43

  14. Landsberg et al., Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation. Nature 2012 490:412

  15. Barckhausen et al., Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair. Oncogene 2013, 1-11

  16. R. Allami, Influence of the chemokine CXCL12 on the progression and the signalling in colorectal cancer; 2013 (MSc thesis)

  17. Harris et al., BMCC1 Is an AP-2 Associated Endosomal Protein in Prostate Cancer Cells; 2013 PLOS One 8(9): e73880

  18. Smart CE, Morrison BJ, Saunus JM, Vargas AC, Keith P, Reid L, Wockner L, Amiri MA, Sarkar D, Simpson PT, Clarke C, Schmidt CW, Reynolds BA, Lakhani SR, Lopez JA. In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity. PLoS One. 2013 Jun 4;8(6):e64388.

  19. Hosein AN, Song S, McCart Reed AE, Jayanthan J, Reid LE, Kutasovic JR, Cummings MC, Waddell N, Lakhani SR, Chenevix-Trench G, Simpson PT. Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis. Lab Invest. 2013 Jun;93(6):701-10. doi: 10.1038/labinvest.2013.

  20. Krishnan K, Steptoe AL, Martin HC, Pattabiraman DR, Nones K, Waddell N, Mariasegaram M, Simpson PT, Lakhani SR, Vlassov A, Grimmond SM, Cloonan N. miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA. 2013 Dec;19(12):1767-80.

  21. Al-Ejeh F, Shi W, Miranda M, Simpson PT, Vargas AC, Song S, Wiegmans AP, Swarbrick A, Welm AL, Brown MP, Chenevix-Trench G, Lakhani SR, Khanna KK. Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor. J Nucl Med. 2013 Jun;54(6):913-21.

  22. Krishnan K, Steptoe AL, Martin HC, Wani S, Nones K, Waddell N, Mariasegaram M, Simpson PT, Lakhani SR, Gabrielli B, Vlassov A, Cloonan N, Grimmond SM. MicroRNA-182-5p targets a network of genes involved in DNA repair. RNA. 2013 Feb;19(2):230-42

  23. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Dunning AM. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics. April 2013 45, 371–384

  24. Amy E McCart Reed, Sarah Song, Jamie R Kutasovic, Lynne E Reid, Jordan Valle, Ana Cristina Vargas, Chanel E Smart, Peter T Simpson (2013). Thrombospondin-4 expression is activated during the stomal response to invasive breast cancer. Virchows Archiv, 2013 Oct; 463(4):535-45

  25. Henriquez NV, Forshew T, Tatevossian R, Ellis M, Richard-Loendt A, Rogers H, Jacques TS, Reitboeck PG, Pearce K, Sheer D, Grundy R, Brandner S. Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro. Cancer Research, 2013 Sep 15;73(18):5834-44.

  26. Rogers HA, Ward JH, Miller S, Lowe J, Coyle B, Grundy RG. The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs) British Journal of Cancer. 2013; 108: 2130-2141

  27. Karsa M1, Dalla Pozza L, Venn NC, Law T, Shi R, Giles JE, Bahar AY, Cross S, Catchpoole D, Haber M, Marshall GM, Norris MD, Sutton R. Improving  the identification of high risk precursor B acute lymphoblastic leukemia patients with earlier quantification of minimal residual disease. PLoS One. 2013 Oct 11;8(10):e76455.

  28. Couch FJ, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker KB, Soucy P, Fredericksen Z, Barrowdale D, Dennis J, Gaudet MM, Dicks E, Kosel M, Healey S, Sinilnikova OM, Lee A, Bacot F, Vincent D, Hogervorst FB, Peock S, Stoppa-Lyonnet D, Jakubowska A; kConFab Investigators, Radice P, Schmutzler RK; SWE-BRCA, Domchek SM, Piedmonte M, Singer CF, Friedman E, Thomassen M; Ontario Cancer Genetics Network, Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Greene MH, Karlan BY, Garber J, Phelan CM, Weitzel JN, Montagna M, Olah E, Andrulis IL, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Nevanlinna H, Osorio A, Terry MB, Daly MB, van Rensburg EJ, Hamann U, Ramus SJ, Toland AE, Caligo MA, Olopade OI, Tung N, Claes K, Beattie MS, Southey MC, Imyanitov EN, Tischkowitz M, Janavicius R, John EM, Kwong A, Diez O, Balmaña J, Barkardottir RB, Arun BK, Rennert G, Teo SH, Ganz PA, Campbell I, van der Hout AH, van Deurzen CH, Seynaeve C, Gómez Garcia EB, van Leeuwen FE, Meijers-Heijboer HE, Gille JJ, Ausems MG, Blok MJ, Ligtenberg MJ, Rookus MA, Devilee P, Verhoef S, van Os TA, Wijnen JT; HEBON; EMBRACE, Frost D, Ellis S, Fineberg E, Platte R, Evans DG, Izatt L, Eeles RA, Adlard J, Eccles DM, Cook J, Brewer C, Douglas F, Hodgson S, Morrison PJ, Side LE, Donaldson A, Houghton C, Rogers MT, Dorkins H, Eason J, Gregory H, McCann E, Murray A, Calender A, Hardouin A, Berthet P, Delnatte C, Nogues C, Lasset C, Houdayer C, Leroux D, Rouleau E, Prieur F, Damiola F, Sobol H, Coupier I, Venat-Bouvet L, Castera L, Gauthier-Villars M, Léoné M, Pujol P, Mazoyer S, Bignon YJ; GEMO Study Collaborators, Zlowocka-Perlowska E, Gronwald J, Lubinski J, Durda K, Jaworska K, Huzarski T, Spurdle AB, Viel A, Peissel B, Bonanni B, Melloni G, Ottini L, Papi L, Varesco L, Tibiletti MG, Peterlongo P, Volorio S, Manoukian S, Pensotti V, Arnold N, Engel C, Deissler H, Gadzicki D, Gehrig A, Kast K, Rhiem K, Meindl A, Niederacher D, Ditsch N, Plendl H, Preisler-Adams S, Engert S, Sutter C, Varon-Mateeva R, Wappenschmidt B, Weber BH, Arver B, Stenmark-Askmalm M, Loman N, Rosenquist R, Einbeigi Z, Nathanson KL, Rebbeck TR, Blank SV, Cohn DE, Rodriguez GC, Small L, Friedlander M, Bae-Jump VL, Fink-Retter A, Rappaport C, Gschwantler-Kaulich D, Pfeiler G, Tea MK, Lindor NM, Kaufman B, Shimon Paluch S, Laitman Y, Skytte AB, Gerdes AM, Pedersen IS, Moeller ST, Kruse TA, Jensen UB, Vijai J, Sarrel K, Robson M, Kauff N, Mulligan AM, Glendon G, Ozcelik H, Ejlertsen B, Nielsen FC, Jønson L, Andersen MK, Ding YC, Steele L, Foretova L, Teulé A, Lazaro C, Brunet J, Pujana MA, Mai PL, Loud JT, Walsh C, Lester J, Orsulic S, Narod SA, Herzog J, Sand SR, Tognazzo S, Agata S, Vaszko T, Weaver J, Stavropoulou AV, Buys SS, Romero A, de la Hoya M, Aittomäki K, Muranen TA, Duran M, Chung WK, Lasa A, Dorfling CM, Miron A; BCFR, Benitez J, Senter L, Huo D, Chan SB, Sokolenko AP, Chiquette J, Tihomirova L, Friebel TM, Agnarsson BA, Lu KH, Lejbkowicz F, James PA, Hall P, Dunning AM, Tessier D, Cunningham J, Slager SL, Wang C, Hart S, Stevens K, Simard J, Pastinen T, Pankratz VS, Offit K, Easton DF, Chenevix-Trench G, Antoniou AC; CIMBA. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet 2013 9(3): 1003212

  29. Ella R. Thompson, Simone M. Rowley, Sarah Sawyer, kConFab, Diana M. Eccles, Alison H. Trainer, Gillian Mitchell, Paul A. James, Ian G. Campbell Analysis of RAD51D in Ovarian Cancer Patients and Families with a History of Ovarian or Breast Cancer PLoS One 2013 8(1): e54772

  30. Teo ZL, Park DJ, Provenzano E, Chatfield CA, Odefrey FA, Nguyen-Dumont T; kConFab, Dowty JG, Hopper JL, Winship I, Goldgar DE, Southey MC. Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families. Breast Cancer Res. 2013 15(1): R17

  31. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N; Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM; kConFab Investigators; Australian Ovarian Cancer Study Group, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, Müller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labrèche F, Dumont M, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Brüning T; GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J, Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Bogdanova NV, Antonenkova NN, Dörk T, Kristensen VN, Anton-Culver H, Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013 45(4): 353-61

  32. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S, Baynes C, Bolla MK, Wang Q, Dennis J, McGuffog L, Barrowdale D, Lee A, Healey S, Lush M, Tessier DC, Vincent D, Bacot F; Australian Cancer Study; Australian Ovarian Cancer Study; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab); Gene Environment Interaction and Breast Cancer (GENICA); Swedish Breast Cancer Study (SWE-BRCA); Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE); Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO), Vergote I, Lambrechts S, Despierre E, Risch HA, González-Neira A, Rossing MA, Pita G, Doherty JA, Alvarez N, Larson MC, Fridley BL, Schoof N, Chang-Claude J, Cicek MS, Peto J, Kalli KR, Broeks A, Armasu SM, Schmidt MK, Braaf LM, Winterhoff B, Nevanlinna H, Konecny GE, Lambrechts D, Rogmann L, Guénel P, Teoman A, Milne RL, Garcia JJ, Cox A, Shridhar V, Burwinkel B, Marme F, Hein R, Sawyer EJ, Haiman CA, Wang-Gohrke S, Andrulis IL, Moysich KB, Hopper JL, Odunsi K, Lindblom A, Giles GG, Brenner H, Simard J, Lurie G, Fasching PA, Carney ME, Radice P, Wilkens LR, Swerdlow A, Goodman MT, Brauch H, Garcia-Closas M, Hillemanns P, Winqvist R, Dürst M, Devilee P, Runnebaum I, Jakubowska A, Lubinski J, Mannermaa A, Butzow R, Bogdanova NV, Dörk T, Pelttari LM, Zheng W, Leminen A, Anton-Culver H, Bunker CH, Kristensen V, Ness RB, Muir K, Edwards R, Meindl A, Heitz F, Matsuo K, du Bois A, Wu AH, Harter P, Teo SH, Schwaab I, Shu XO, Blot W, Hosono S, Kang D, Nakanishi T, Hartman M, Yatabe Y, Hamann U, Karlan BY, Sangrajrang S, Kjaer SK, Gaborieau V, Jensen A, Eccles D, Høgdall E, Shen CY, Brown J, Woo YL, Shah M, Azmi MA, Luben R, Omar SZ, Czene K, Vierkant RA, Nordestgaard BG, Flyger H, Vachon C, Olson JE, Wang X, Levine DA, Rudolph A, Weber RP, Flesch-Janys D, Iversen E, Nickels S, Schildkraut JM, Silva Idos S, Cramer DW, Gibson L, Terry KL, Fletcher O, Vitonis AF, van der Schoot CE, Poole EM, Hogervorst FB, Tworoger SS, Liu J, Bandera EV, Li J, Olson SH, Humphreys K, Orlow I, Blomqvist C, Rodriguez-Rodriguez L, Aittomäki K, Salvesen HB, Muranen TA, Wik E, Brouwers B, Krakstad C, Wauters E, Halle MK, Wildiers H, Kiemeney LA, Mulot C, Aben KK, Laurent-Puig P, Altena AM, Truong T, Massuger LF, Benitez J, Pejovic T, Perez JI, Hoatlin M, Zamora MP, Cook LS, Balasubramanian SP, Kelemen LE, Schneeweiss A, Le ND, Sohn C, Brooks-Wilson A, Tomlinson I, Kerin MJ, Miller N, Cybulski C, Henderson BE, Menkiszak J, Schumacher F, Wentzensen N, Le Marchand L, Yang HP, Mulligan AM, Glendon G, Engelholm SA, Knight JA, Høgdall CK, Apicella C, Gore M, Tsimiklis H, Song H, Southey MC, Jager A, den Ouweland AM, Brown R, Martens JW, Flanagan JM, Kriege M, Paul J, Margolin S, Siddiqui N, Severi G, Whittemore AS, Baglietto L, McGuire V, Stegmaier C, Sieh W, Müller H, Arndt V, Labrèche F, Gao YT, Goldberg MS, Yang G, Dumont M, McLaughlin JR, Hartmann A, Ekici AB, Beckmann MW, Phelan CM, Lux MP, Permuth-Wey J, Peissel B, Sellers TA, Ficarazzi F, Barile M, Ziogas A, Ashworth A, Gentry-Maharaj A, Jones M, Ramus SJ, Orr N, Menon U, Pearce CL, Brüning T, Pike MC, Ko YD, Lissowska J, Figueroa J, Kupryjanczyk J, Chanock SJ, Dansonka-Mieszkowska A, Jukkola-Vuorinen A, Rzepecka IK, Pylkäs K, Bidzinski M, Kauppila S, Hollestelle A, Seynaeve C, Tollenaar RA, Durda K, Jaworska K, Hartikainen JM, Kosma VM, Kataja V, Antonenkova NN, Long J, Shrubsole M, Deming-Halverson S, Lophatananon A, Siriwanarangsan P, Stewart-Brown S, Ditsch N, Lichtner P, Schmutzler RK, Ito H, Iwata H, Tajima K, Tseng CC, Stram DO, van den Berg D, Yip CH, Ikram MK, Teh YC, Cai H, Lu W, Signorello LB, Cai Q, Noh DY, Yoo KY, Miao H, Iau PT, Teo YY, McKay J, Shapiro C, Ademuyiwa F, Fountzilas G, Hsiung CN, Yu JC, Hou MF, Healey CS, Luccarini C, Peock S, Stoppa-Lyonnet D, Peterlongo P, Rebbeck TR, Piedmonte M, Singer CF, Friedman E, Thomassen M, Offit K, Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Garber J, Narod SA, Weitzel JN, Montagna M, Olah E, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Imyanitov EN, Tihomirova L, Arun BK, Campbell I, Mensenkamp AR, van Asperen CJ, van Roozendaal KE, Meijers-Heijboer H, Collée JM, Oosterwijk JC, Hooning MJ, Rookus MA, van der Luijt RB, Os TA, Evans DG, Frost D, Fineberg E, Barwell J, Walker L, Kennedy MJ, Platte R, Davidson R, Ellis SD, Cole T, Bressac-de Paillerets B, Buecher B, Damiola F, Faivre L, Frenay M, Sinilnikova OM, Caron O, Giraud S, Mazoyer S, Bonadona V, Caux-Moncoutier V, Toloczko-Grabarek A, Gronwald J, Byrski T, Spurdle AB, Bonanni B, Zaffaroni D, Giannini G, Bernard L, Dolcetti R, Manoukian S, Arnold N, Engel C, Deissler H, Rhiem K, Niederacher D, Plendl H, Sutter C, Wappenschmidt B, Borg A, Melin B, Rantala J, Soller M, Nathanson KL, Domchek SM, Rodriguez GC, Salani R, Kaulich DG, Tea MK, Paluch SS, Laitman Y, Skytte AB, Kruse TA, Jensen UB, Robson M, Gerdes AM, Ejlertsen B, Foretova L, Savage SA, Lester J, Soucy P, Kuchenbaecker KB, Olswold C, Cunningham JM, Slager S, Pankratz VS, Dicks E, Lakhani SR, Couch FJ, Hall P, Monteiro AN, Gayther SA, Pharoah PD, Reddel RR, Goode EL, Greene MH, Easton DF, Berchuck A, Antoniou AC, Chenevix-Trench G, Dunning AM. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet 2013 45(4): 371-84

  33. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J, Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guénel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensen V, Swerdlow A, Anton-Culver H, Dörk T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Southey MC, Park DJ, Hammet F, Stone J, Veer LJ, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, Dos Santos Silva I, Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Müller H, Arndt V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD; Gene ENvironmental Interaction and breast CAncer (GENICA) Network, Muranen TA, Aittomäki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R; kConFab Investigators, Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labrèche F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollenaar RA, Seynaeve CM, Kriege M, Hooning MJ, van den Ouweland AM, van Deurzen CH, Lu W, Gao YT, Cai H, Balasubramanian SP, Cross SS, Reed MW, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, González-Neira A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ, Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimiklis H, Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B, Schmutzler RK, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J, Turnbull C; Familial Breast Cancer Study (FBCS), Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F; Australian Breast Cancer Tissue Bank (ABCTB) Investigators, Olswold C, Slager S, Pilarski R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ, Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R, Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R, Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD, Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR, Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME, Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF, Haiman CA, Kraft P. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 2013 45(4): 392-8

  34. French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O’Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Conroy D, Dennis J, Bolla MK, Wang Q, Hopper JL, Southey MC, Schmidt MK, Broeks A, Verhoef S, Cornelissen S, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Loehberg CR, Ekici AB, Beckmann MW, Peto J, dos Santos Silva I, Johnson N, Aitken Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Zamora MP, Arias Perez JI, Benitez J, Anton-Culver H, Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Engel C, Brauch H, Hamann U, Justenhoven C; GENICA Network, Aaltonen K, Heikkilä P, Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Sueta A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D, Peeters S, Smeets A, Floris G, Chang-Claude J, Rudolph A, Nickels S, Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Sardella D, Couch FJ, Wang X, Pankratz VS, Lee A, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, Ng CH, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devilee P, Seynaeve C, García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring D, Schoof N, Hooning MJ, Martens JW, Collée JM, Tilanus-Linthorst M, Hall P, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A, Balasubramanian SP, Blot W, Signorello LB, Cai Q, Pharoah PD, Healey CS, Shah M, Pooley KA, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Sng JH, Sim X, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, McKay J, Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK, Shen CY, Hsiung CN, Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N, Schoemaker MJ, Ponder BA, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM. Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013 92(4): 489-503

  35. Barnes DR, Barrowdale D, Beesley J, Chen X; kConFab Investigators; Australian Ovarian Cancer Study Group, James PA, Hopper JL, Goldgar D, Chenevix-Trench G, Antoniou AC, Mitchell G. Estimating single nucleotide polymorphism associations using pedigree data: applications to breast cancer. Br J Cancer 2013 Jun 11

  36. Gaudet MM, Kuchenbaecker KB, Vijai J, Klein RJ, Kirchhoff T, McGuffog L, Barrowdale D, Dunning AM, Lee A, Dennis J, Healey S, Dicks E, Soucy P, Sinilnikova OM, Pankratz VS, Wang X, Eldridge RC, Tessier DC, Vincent D, Bacot F, Hogervorst FB, Peock S, Stoppa-Lyonnet D; KConFab Investigators, Peterlongo P, Schmutzler RK, Nathanson KL, Piedmonte M, Singer CF, Thomassen M; Ontario Cancer Genetics Network, Hansen Tv, Neuhausen SL, Blanco I, Greene MH, Garber J, Weitzel JN, Andrulis IL, Goldgar DE, D’Andrea E, Caldes T, Nevanlinna H, Osorio A, van Rensburg EJ, Arason A, Rennert G, van den Ouweland AM, van der Hout AH, Kets CM, Aalfs CM, Wijnen JT, Ausems MG; HEBON; EMBRACE, Frost D, Ellis S, Fineberg E, Platte R, Evans DG, Jacobs C, Adlard J, Tischkowitz M, Porteous ME, Damiola F; GEMO Study Collaborators, Golmard L, Barjhoux L, Longy M, Belotti M, Ferrer SF, Mazoyer S, Spurdle AB, Manoukian S, Barile M, Genuardi M, Arnold N, Meindl A, Sutter C, Wappenschmidt B, Domchek SM, Pfeiler G, Friedman E, Jensen UB, Robson M, Shah S, Lazaro C, Mai PL, Benitez J, Southey MC, Schmidt MK, Fasching PA, Peto J, Humphreys MK, Wang Q, Michailidou K, Sawyer EJ, Burwinkel B, Guénel P, Bojesen SE, Milne RL, Brenner H, Lochmann M; GENICA Network, Aittomäki K, Dörk T, Margolin S, Mannermaa A, Lambrechts D, Chang-Claude J, Radice P, Giles GG, Haiman CA, Winqvist R, Devillee P, García-Closas M, Schoof N, Hooning MJ, Cox A, Pharoah PD, Jakubowska A, Orr N, González-Neira A, Pita G, Alonso MR, Hall P, Couch FJ, Simard J, Altshuler D, Easton DF, Chenevix-Trench G, Antoniou AC, Offit K. Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. PLoS Genet 2013 9(3): e1003173

  37. Teo ZL, Provenzano E, Dite GS, Park DJ, Apicella C, Sawyer SD, James PA, Mitchell G, Trainer AH, Lindeman GJ, Shackleton K, Cicciarelli L; kConFab, Buys SS, Andrulis IL, Mulligan AM, Glendon G, John EM, Terry MB, Daly M, Odefrey FA, Nguyen-Dumont T, Giles GG, Dowty JG, Winship I, Goldgar DE, Hopper JL, Southey MC. Tumour morphology predicts PALB2 germline mutation status. Br J Cancer 2013 109(1): 154-63

  38. Collins IM, Milne RL, McLachlan SA, Friedlander M, Hickey M, Weideman PC, Birch KE, Hopper JL, Phillips KA. Do BRCA1 and BRCA2 Mutation Carriers Have Earlier Natural Menopause Than Their Noncarrier Relatives? Results From the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer. J Clin Oncol 2013

  39. Phillips KA, Milne RL, Rookus MA, Daly MB, Antoniou AC, Peock S, Frost D, Easton DF, Ellis S, Friedlander ML, Buys SS, Andrieu N, Noguès C, Stoppa-Lyonnet D, Bonadona V, Pujol P, McLachlan SA, John EM, Hooning MJ, Seynaeve C, Tollenaar RA, Goldgar DE, Terry MB, Caldes T, Weideman PC, Andrulis IL, Singer CF, Birch K, Simard J, Southey MC, Olsson HL, Jakubowska A, Olah E, Gerdes AM, Foretova L, Hopper JL. Tamoxifen and Risk of Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers. J Clin Oncol 2013 31(25): 3091-3099

  40. John EM, McGuire V, Thomas D, Haile R, Ozcelik H, Milne RL, Felberg A, West DW, Miron A, Knight JA, Terry MB, Daly M, Buys SS, Andrulis IL, Hopper JL, Southey MC, Giles GG, Apicella C, Thorne H; for the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Whittemore AS. Diagnostic Chest X-Rays and Breast Cancer Risk before Age 50 Years for BRCA1 and BRCA2 Mutation Carriers. Cancer Epidemiol Biomarkers Prev 2013 22(9): 1547-1556

  41. Rudolph A, Hein R, Lindström S, Beckmann L, Behrens S, Liu J, Aschard H, Bolla MK, Wang J, Truong T, Cordina-Duverger E, Menegaux F, Brüning T, Harth V; GENICA Network, Severi G, Baglietto L, Southey M, Chanock SJ, Lissowska J, Figueroa JD, Eriksson M, Humpreys K, Darabi H, Olson JE, Stevens KN, Vachon CM, Knight JA, Glendon G, Mulligan AM, Ashworth A, Orr N, Schoemaker M, Webb PM; kConFab Investigators; AOCS Management Group, Guénel P, Brauch H, Giles G, García-Closas M, Czene K, Chenevix-Trench G, Couch FJ, Andrulis IL, Swerdlow A, Hunter DJ, Flesch-Janys D, Easton DF, Hall P, Nevanlinna H, Kraft P, Chang-Claude J; Breast Cancer Association Consortium. Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study. Endocr Relat Cancer. 2013 20(6): 875-87

  42. Deb S, Do H, Byrne D, Jene N; kConFab Investigators, Dobrovic A, Fox SB. PIK3CA mutations are frequently observed in BRCAX but not BRCA2 -associated male breast cancer. Breast Cancer Res. 2013 15(4): R69

  43. Nickels S, Truong T, Hein R, Stevens K, Buck K, Behrens S, Eilber U, Schmidt M, Häberle L, Vrieling A, Gaudet M, Figueroa J, Schoof N, Spurdle AB, Rudolph A, Fasching PA, Hopper JL, Makalic E, Schmidt DF, Southey MC, Beckmann MW, Ekici AB, Fletcher O, Gibson L, Silva Idos S, Peto J, Humphreys MK, Wang J, Cordina-Duverger E, Menegaux F, Nordestgaard BG, Bojesen SE, Lanng C, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Müller H, Arndt V, Stegmaier C, Brauch H, Brüning T, Harth V; Genica Network, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab; AOCS Management Group, Lambrechts D, Smeets D, Neven P, Paridaens R, Flesch-Janys D, Obi N, Wang-Gohrke S, Couch FJ, Olson JE, Vachon CM, Giles GG, Severi G, Baglietto L, Offit K, John EM, Miron A, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Chanock SJ, Lissowska J, Liu J, Cox A, Cramp H, Connley D, Balasubramanian S, Dunning AM, Shah M, Trentham-Dietz A, Newcomb P, Titus L, Egan K, Cahoon EK, Rajaraman P, Sigurdson AJ, Doody MM, Guénel P, Pharoah PD, Schmidt MK, Hall P, Easton DF, Garcia-Closas M, Milne RL, Chang-Claude J. Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors. PLoS Genet. 2013 9(3): e1003284

  44. Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC, Chenevix-Trench G; kConFab Investigators; Australian Ovarian Cancer Study Group, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Bojesen SE, Nordestgaard BG, Flyger H, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Wang X, Olson JE, Vachon C, Purrington K, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Dunning AM, Shah M, Guénel P, Truong T, Sanchez M, Mulot C, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, Collée JM, Jager A, Cox A, Brock IW, Reed MW, Devilee P, Tollenaar RA, Seynaeve C, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Dumont M, Soucy P, Dörk T, Bogdanova NV, Hamann U, Försti A, Rüdiger T, Ulmer HU, Fasching PA, Häberle L, Ekici AB, Beckmann MW, Fletcher O, Johnson N, Dos Santos Silva I, Peto J, Radice P, Peterlongo P, Peissel B, Mariani P, Giles GG, Severi G, Baglietto L, Sawyer E, Tomlinson I, Kerin M, Miller N, Marme F, Burwinkel B, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Alnæs GG, Kristensen V, Børresen-Dale AL, García-Closas M, Chanock SJ, Lissowska J, Figueroa JD, Schmidt MK, Broeks A, Verhoef S, Rutgers EJ, Brauch H, Brüning T, Ko YD; The GENICA Network, Couch FJ, Toland AE; The TNBCC, Yannoukakos D, Pharoah PD, Hall P, Benítez J, Malats N, Easton DF. A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium. Hum Mol Genet. 2013 Nov 28: Epub

  45. Collins IM, Milne RL, Weideman PC, McLachlan SA, Friedlander ML, Kathleen Cuningham Foundation Consortium For Research Into Familial Breast Cancer KC, Hopper JL, Phillips KA. Preventing breast and ovarian cancers in high-risk BRCA1 and BRCA2 mutation carriers. Med J Aust. 2013 199(10): 680-3

 

Conference Abstracts

  1. deFazio A. Time for t (1, 2 and 3): Translational cancer research and the SW-TCRC. Second Crown Princess Mary Cancer Centre Symposium; Sydney; 2013.

  2. deFazio A, Emmanuel C, Chiew YE, Etemadmoghadam D, George J, Sharma R, Russell P, Kennedy C, Fereday S, Hung J, Galletta L, Hogg R, Wain GV, Brand A, Anglesio M, MacConaill L, Hunter S, Campbell I, Dobrovic A, Wong S, Do H, Australian Ovarian Cancer Study Group, Harnett PR and  Bowtell DDL. Distinguishing clinico-genomic features of Ras-pathway and TP53 mutated serous ovarian carcinoma. Victorian Comprehensive Cancer Centre Ovarian Cancer Symposium 2013, Melbourne, August 5-7, 2013.

  3. Kennedy C, Chiew YE, Hung JA, Kay LC, Sharma R,  Balleine R, Achan A,  Stenlake A, Wain GV, Brand AH, Hogg RJ, Leary J, Harnett PR and deFazio A. GynBiobank quality control: systemic pathology review and RNA integrity of cryopreserved tumour tissue. Australasain Biospecimen Network Association 11th Annual Meeting, Melbourne, 14-15 November, 2013.

  4. Marsh D, deFazio A, Clarkson, A, Kennedy C, AOCS, Gard G, Gill A. Loss of histone H2B mono-ubiquitination in ovarian cancer-new therapeutic targeting opportunities based on chromatin relaxation. 5th Annual Ubiquitin Drug Discovery & Diagnostics Conference, Philadelphia, USA, July 22-24, 2013

  5. Gao B, Nieuweboer AJM, Xu H, Beesley J, Moghaddam-Helmantel IMG, deGraan A-JM, deBruijn P, Gurney H, Johnatty SE, Beale P, Chenevix-Trench G, Balleine RL, Mathijssen RHJ, Harnett PR, deFazio A. Influence of ABCB1 polymorphisms on paclitaxel pharmacokinetics in ovarian cancer patients. AACR Special Conference Advances in Ovarian Cancer Research: From Concept to Clinic; Miami, Fl, USA; 2013.

  6. Henderson M, Hedditch EL, Russell AR, Gao B, Lu Y, Flemming C, Williams RT, Emmanuel C, Beesley J, Johnatty S, George J, Harnett P, AOCS Group, MacGregor S, Bowtell DD, Chenevix-Trench G, DeFazio A, Norris MD, Haber M. Association of ABCA1 cholesterol transporter with poor outcome and aggressive phenotype in serous ovarian cancer. Lorne Cancer Conference, 14th-16th February, 2013, Lorne, VIC

  7. Jung MS, Russell AJ, Hedditch EL, DeFazio A, Ward R, Haber M, Norris MD, Henderson MJ, AOCS Group. Association of Myc oncogene family expression with patient outcome in ovarian and colorectal carcinomas. Lorne Cancer Conference, 14th-16th February, 2013, Lorne, VIC.

  8. Emmanuel C, Chiew Y-E, Etemadmoghadam D, Sharma R, Kennedy C, Fereday S, Hung J, Galletta L, Hogg R, Wain GV, Brand A, Anglesio M, MacConaill L, Palescandolo E, Jones R, Hunter S, Campbell I, Dobrovic A, Wong S, Australian Ovarian Cancer Study Group, Harnett PR, Bowtell DDL, deFazio A. NRAS mutations in serous ovarian cancer. Hospital Week, Westmead Hospital Westmead; 2013.

  9. Ben Green, Jodie Saunus, Amy McCart-Reed, Georgia Chenevix-Trench, Kum Kum Khana, Chanel Smart, Colleen Niland, Kaltin Ferguson, Peter Simpson and Sunil Lakhani. Prospective Study of Patients with Breast Tumours and Discovery of potential biomarkers and therapeutic Options.  Australian Biospecimen Researchers Network Annual meeting. 2013

  10. Kaltin Ferguson1, Ana Cristina Vargas, Amy McCart-Reed, Chanel Smart, Peter Simpson and Sunil Lakhani1 BRISBANE BREAST BANK.  QLD. 2013

  11. A. Raghavendra1, A C. Vargus, J. Madore, M. Mariasegaram, L. Reed, J. Kutasovic, C. Niland, M. Cumming, L. Da Silva,  E. Bhutada, S. Peyton, T M. Hauer, S. Song, C E. Smart1, J. Saunus1, S. R Lakhani2. Amy E McCart Reed, Sarah Song, Jamie R Kutasovic, Lynne E Reid, Jordan Valle, Ana Cristina Vargas, Chanel E Smart, Peter T Simpson.. ROLE OF SOX10 IN BREAST CANCER. Australian society of medical research conference in Brisbane. (2013).

  12. Amy E McCart Reed, Sarah Song, Jamie R Kutasovic, Lynne E Reid, Jordan Valle, Ana Cristina Vargas, Chanel E Smart, Peter T Simpson. Thrombospondin-4 expression is activated during the stomal response to invasive breast cancer. Australian Society of Medical Research conference in Brisbane. 2013

  13. A. Raghavendra, A C. Vargas, J. Madore, M. Mariasegaram, L. Reid, J. Kutasovic, C. Niland, M. Cumming, L. Da Silva,  E. Bhutada, S. Peyton, T M. Hauer, S. Song, P. Simpson, C E. Smart, J. Saunus, S. R Lakhani. SOX10 as a prognostic biomarker in triple negative and basal-like breast cancer.. The Australian society of stem cell research conference. 2013

  14. A. Raghavendra, A C. Vargas, J. Madore, M. Mariasegaram, L. Reid, J. Kutasovic, C. Niland, M. Cumming, L. Da Silva,  E. Bhutada, S. Peyton, T M. Hauer, S. Song, P. Simpson, C E. Smart, J. Saunus, S. R Lakhani. SOX10 as a prognostic biomarker in triple negative and basal-like breast cancer. Australian Breast Cancer Conference. Walter and Eliza Hall Institute of Medical Research, Melbourne, 2013

  15. Jamie Kutasovic, Amy McCart Reed, Ana Cristina Vargas, Janani Jayanthan, Lynne Reid, Leo Da Silva, Margaret Cummings, Alan Porter, Elizabeth Evans, Sunil Lakhani, Peter T Simpson. Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. Australian Breast Cancer Conference. Walter and Eliza Hall Institute of Medical Research, Melbourne, 2013

  16. Jodi M. Saunus, Michael C.J. Quinn, Ann-Marie Patch, John V. Pearson, Peter J. Bailey, Katia Nones, David Miller, Peter J. Wilson, Mythily Mariasegaram, Queenie Lau, Teresa Withers, Rosalind L. Jeffree, Lynne Reid, Amy McCart Reed, Leonard Da Silva, Colleen M. Niland, Margaret C. Cummings, Tim Bruxner, Angelika Christ, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Craig Nourse, Ehsan Nourbakhsh, Shivangi Wani, Matthew Anderson, Lynn Fink, Oliver Holmes, Stephen Kazakoff, Conrad Leonard, Felicity Newell, Darrin Taylor, Nick Waddell, Scott Wood, Christina Xu, Karin Khassahn, Vairavan Narayanan, Nur Aishah Taib, Soo-Hwang Teo, Yock Ping Chow, kConFab, Parmjit Jat, Sebastian Brandner, Kwun Fong, Kum Kum Khanna, Georgia Chenevix-Trench, Sean M. Grimmond, Peter T. Simpson, Nicola Waddell and Sunil R. Lakhani. Genomic landscape of brain metastasis from breast cancer.  Australian Breast Cancer Conference. Walter and Eliza Hall Institute of Medical Research, Melbourne, 2013

  17. M.C.J. Quinn, J.M Saunus, D. Miller, K. Nones, A.M. Patch, M. Mariasegaram, Q. Lau, L. Jeffree, J.V. Pearson, G. Chenevix-Trench, S.M Grimmond, P.T Simpson, N. Waddell and S.R. Lakhani. Genomic analysis of human brain metastases: an integrative approach. Lorne Cancer Conference. Victoria. 2013

  18. M.C.J. Quinn, J.M. Saunus, D. Miller, K. Nones, A.M. Patch, P.J. Bailey, M. Mariasegaram, Q. Lau3, L. Jeffree, J.V. Pearson, G. Chenevix-Trench, S.M. Grimmond, P.T. Simpson, N. Waddell and S.R. Lakhani. Genomic landscape of human brain metastasis.  AMATA. 2013

  19. Jamie Kutasovic, Amy McCart Reed, Ana Cristina Vargas, Janani Jayanthan, Lynne Reid, Leo Da Silva, Margaret Cummings, Alan Porter, Elizabeth Evans, Sunil Lakhani, Peter T Simpson Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. Australian Breast Cancer Conference, Melbourne. 2013

 

 

The following research has been published in 2011-2012 using data or tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren Aoude, Varsha Tembe, Gulietta Pupo, Cathy Lanagan, Candace Carter, Linda O’Connor, Michael O’Rourke, Richard Scolyer, Graham Mann, Christopher Schmidt, Adrian Herington, and Nicholas Hayward (2012) A high throughput panel for identifying clinically-relevant mutation profiles in melanoma. Molecular Cancer Therapeutics, 11(4):888-97.
  • Ken Dutton-Regester, Lauren Aoude, Derek J. Nancarrow, Mitchell S Stark, Linda O’Connor, Cathy Lanagan, Gulietta M. Pupo, Varsha Tembe, Candace D. Carter, Michael O’Rourke, Richard A. Scolyer, Graham Mann, Chris Schmidt, Adrian Herington, Nicholas K. Hayward. Identification of TFG (TRK fused gene) as a putative metastatic melanoma tumour suppressor gene. (2012) Genes, Chromosomes and Cancer 51(5):452-461
  • Bonazzi VF, Nancarrow DJ, Stark MS, Moser RJ, Boyle GM, Aoude LG, Schmidt C, Hayward NK. (2011) Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1as Genes Frequently Silenced by Methylation in Melanoma. PLoS ONE 6(10): e26121. doi:10.1371/journal.pone.0026121
  • Mitchell S. Stark, Susan L. Woods, Michael G. Gartside, Vanessa F. Bonazzi, Ken Dutton-Regester, Lauren G. Aoude, Donald Chow, Chris Sereduk, Natalie M. Niemi, Nanyun Tang, Jonathan J. Ellis, Jeffrey Reid, Victoria Zismann, Sonika Tyagi, Donna Muzny, Irene Newsham, YuanQing Wu, Jane M. Palmer, Thomas Pollak, David Youngkin, Bradford R. Brooks, Catherine Lanagan, Christopher W. Schmidt, Bostjan Kobe, Jeffrey P. MacKeigan, Hongwei Yin, Kevin M. Brown, Richard Gibbs, Jeffrey Trent, Nicholas K. Hayward. (2011) Frequent MAP3K5/9 somatic mutations in metastatic melanoma identified by exome sequencing. Nature Genetics, Dec 25;44(2):165-9
  • Creaney J, Dick Ian M, Yeoman D, Wong S, Robinson BWS. Auto-antibodies to ß-F1-ATPase and Vimentin in Malignant Mesothelioma. PlosOne 2011 6:e26515.
  • Creaney J, Segal A, Musk AW, Skates SJ, Robinson BWS. Mesothelioma Biomarkers- Now and the Future. Journal of Thoracic Oncology 2011 6: S4, 3
  • Tan AL, Worku M, Davies HE, Mishra E, Sadler R, Creaney J, Lansley SM, Varano J, Karabela S, Stathopoulos G, Davies RJO, Lee YCG. Fibroblast growth Factor-9 is upregulated and may be involved in Mesothelioma Disease Pathobiology. Respirology 2011 16: S1, 13
  • Arango D, Williams D, Al-Obaidi S, Dopeso J, Mazzolini R, Corner G, Byun D-S, Murone C, Togel L, Zeps N, Aaltonen L, Iacopetta B and Mariadason JM Am J Pathol. Villin expression is frequently lost in poorly differentiated colon cancer. 2012 Feb 17 [Epub ahead of print]
  • Marianna J. Bledsoe, William E. Grizzle, Brian J. Clark Nikolajs Zeps Genet Med. Implementation Issues and Challenges for Biobanks in the Return of Individual Research Results. 2012 Feb 9.
  • Chew A, Salama P, Robbshaw A, Klopcic B, Zeps N, Platell C, Lawrance IC PLoS OneSPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer 2011
  • Joly Y, Zeps N, Knoppers BM.. Genomic databases access agreements: legal validity and possible sanctions. Human Genetics 2011 Vol 130 issue 3 pages 441-9
  • Tonti-Filippini N, Zeps N. MJA Trade in human tissue products.2011 Vol194.Issue 5 263-5
  • Xiang Guo, Qing-Rong Chen, Young K Song, Jun S Wei and Javed Khan.
    BMC Medical Genomics. Exon array analysis reveals neuroblastoma tumors have distinct alternative splicing patterns according to stage and MYCN amplification status.
    2011 Volume 4 Issue 35.
  • Loh M, Chua D, Yao Y, Soo RA, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R.. Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies? Pharmacogenomics Journal. 2012.26
  • Pérez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grützmann R, Aust D, Rümmele P, Knösel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, Li A, Morgan R, Knight S, Yu J, Stegeman S, Collier LS, ten Hoeve JJ, de Ridder J, Klein AP, Goggins M, Hruban RH, Chang DK, Biankin AV, Grimmond SM; Australian Pancreatic Cancer Genome Initiative, Wessels LF, Wood SA, Iacobuzio-Donahue CA, Pilarsky C, Largaespada DA, Adams DJ, Tuveson DA.
    The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
    Nature. 2012 Apr 29;486(7402):266-70. doi: 10.1038/nature11114.

 

The following research has been published in 2010 using data or tissue specimens supplied by ABN-Oncology-affliated tissue banks:

  • Thomas Dunwell, Luke Hesson, Tibor A Rauch, Lihui Wang, Richard E Clark, Ashraf Dallol, Dean Gentle, Daniel Catchpoole, Eamonn R Maher, Gerd P Pfeifer, Farida Latif A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers Molecular Cancer 2010, 9:44
  • James G Taylor, Adam T Cheuk, Patricia S Tsang, Joon-Yong Chung, Young K Song, Krupa Desai, Yanlin Yu, Qing-Rong Chen, Kushal Shah, Victoria Youngblood, JunFang, Su Yong Kim, Choh Yeung, Lee J. Helman, Arnulfo Mendoza, Vu Ngo, Louis M Staudt, Jun S Wei, Chand Khanna, Daniel Catchpoole, Stephen J Qualman, Stephen M Hewitt, glenn Merlino, Stephen J Chanock and Javed Khan. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models. J Clin Invest. 2009;119(11):3395–3407
  • Platell C, Zeps N, Joseph D, Spry N, Iacopetta B, Caruso V. Tumour banking as part of routine clinical practice. ANZ J Surg. 2010 Apr;80(4):203-4.
  • Ang PW, Loh M, Liem N, Lim PL, Grieu F, Vaithilingam A, Platell C, Yong WP, Iacopetta B, Soong R. Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features. BMC Cancer. 2010 May 21;10:227.
  • Johal H, Faedo M, Faltas J, Lau A, Mousina R, Cozzi P, DeFazio A, Rawlinson W. DNA of mouse mammary tumor virus-like virus is present in human tumors influenced by hormones. J Med Virol 2010; 82: 1044-50
  • Ahmed AA, Etemadmoghadam D, Temple J, Lynch AG, Riad M, Sharma R, Stewart C, Fereday S, Caldas C, deFazio A, Bowtell D, Brenton JD. Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary. J Pathol 2010; 221: 49-56

 

Research published in 2009 using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Taylor, JG, Cheuk AT, Tsang PS, Chung J, Song YK, Desai K, Yu Y, Chen Q, Shah K, Youngblood V, Fang J, Kim SY, Yeung C, Helman LJ, Mendoza A, Ngo V, Staudt LM, Wei JS, Khanna C, Catchpoole D, Qualman SJ, Hewitt SM, Merlino G, Chanock SJ, and Khan J. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models J Clin Invest. 2009;119(11):3395–3407
  • Luke B Hesson, Thomas L Dunwell, Wendy N Cooper, Daniel Catchpoole, Anna T Brini, Raffaella Chiaramonte, Mike Griffiths, Andrew D Chalmers, Eamonn R Maher, Farida Latif The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias Molecular Cancer 2009, 8:42 (2009)
  • Thomas L. Dunwell, Luke B. Hesson, Tatiana Pavlova, Veronika Zabarovska, Daniel Catchpoole, Raffaella Chiaramonte, Anna T. Brini, Mike Griffiths, Eamonn R. Maher, Eugene Zabarovsky, Farida Latif. Epigenetic analysis of childhood acute lymphoblastic leukemia. Epigenetics 4:3, 185-193
  • Thomas L. Dunwell, Rachel E Dickinson, Tatjana Stankovic, Ashraf Dallol, Victoria Weston, Belinda Austen, Daniel Catchpoole, Eamonn R Maher, Farida Latif. Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia. Epigenetics 4:4, 265-269
  • Kadupitige S.R., Leung K.C., Sellmeier J., Sivieng J., Catchpoole D.R., Bain M.E. and Gaëta B.A. MINER: exploratory analysis of gene interaction networks by machine learning from expression data BMC Genomics 2009, 10(Suppl 3):S17
  • Drake J, Shearwood AM, White J, Friis R, Zeps N, Charles A, Dharmarajan A Expression of secreted frizzled-related protein 4 (SFRP4) in primary serous ovarian tumours. Eur J Gynaecol Oncol. 2009;30(2):133-41.
  • Krajewska M, Smith LH, Rong J, Huang X, Hyer ML, Zeps N, Iacopetta B, Linke SP, Olson AH, Reed JC, Krajewski S. Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections. J Histochem Cytochem 2009 57: 649-663
  • Soong R, Shah N, Peh BK, Chong PY, Ng SS, Zeps N, Joseph D, Salto-Tellez M, Iacopetta B, Ito Y. The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome British Journal of Cancer (2009) 100, 676 – 679
  • SC Naumann, WP Roos, E Jost, C Belohlavek, V Lennerz, CW Schmidt, M Christmann and B Kaina Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: reponse related to MGMT, MMR, DSBs, and p53 British Journal of Cancer (2009) 100, 322 – 333
  • Paul Salama, Michael Phillips, Fabienne Grieu, Melinda Morris, Nik Zeps, David Joseph, Cameron Platell, and Barry Iacopetta Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer J Clin Oncol 27:186-192
  • Schofield L, Watson N, Grieu F, Li WQ, Zeps N, Harvey J, Stewart C, Abdo M, Goldblatt J, Iacopetta B. Population-based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial test Int. J. Cancer: 124, 1097–1102 (2009)
  • Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG. Mutation of FOXL2 in granulosa-cell tumours of the ovary N Engl J Med 2009;360:2719-29
  • Etemadmoghadam D, deFazio A, Beroukhim R, Mermel C, George J, Getz G, Tothill R, Okamoto A, Raeder MB, AOCS Study Group, Harnett PR, Lade S, Akslen LA, Tinker A, Locandro B, Alsop K, Chiew Y-E, Traficante N, Fereday S, Johnson D, Fox S, Sellers W, Urashima M, Salvesen HB, Meyerson M and Bowtell D. Integrated genome-wide DNA Copy Number and expression analysis identifies distinct mechanisms of primary chemo-resistance in ovarian carcinomas Clin Cancer Res 2009;15:1417-1427

 

Research published in 2008 using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Nguyen Huu N, Ryder W, Zeps N, Flasza M, Chiu M, Hanby A, Poulsom R, Clarke R, Baron M. Tumour-promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator J Pathol 2008; 216: 93–102
  • Creaney J, Segal A, Sterrett G, Platten MA, Baker E, Murch AR, Nowak AK, Robinson BW, Millward MJ. Overexpression and altered glycosylation of MUC1 in malignant mesothelioma. Br J Cancer 98: 1562-1569
  • Creaney J, Yeoman D, Demelker Y, Segal A, Musk AW, Skates SJ, Robinson BW. Comparison of Osteopontin, Megakaryocyte Potentiating Factor, and Mesothelin Proteins as Markers in the Serum of Patients with Malignant Mesothelioma. Journal of Thoracic Oncology. 3(8):858-864
  • Catchpoole D.R., Guo D., Jiang H., Biesheuvel C. Predicting outcome in childhood acute lymphoblastic leukaemia using gene expression profiling: Prognostication or protocol selection? Blood 2008; 111(4): 2486-2487
  • Margetts C.D.E., Morris M., Astuti D., Gentle D.C., Cascon A., McRonald F.E., Catchpoole D.R., Robledo M., Neumann H.P.H., Latif F. and Maher E.R. Evaluation of a functional epigenetic approach to identify promoter region methylation in phaeochromocytoma Endocrine-Related Cancer (2008) 15 777–786
  • Natrajan R, Warren W, Messahel B, Reis-Filho JS, Brundler MA, Dome JS, Grundy PE, Vujanic G, Pritchard Jones K, Jones C. Complex patterns of chromosome 9 alterations including the p16INK4a locus in Wilms tumours J Clin Pathol 2008;61:95-102
  • Shehata M, Bièche I, Boutros R, Weidenhofer J, Fanayan S, Spalding L, Zeps N, Byth K, Bright RK, Lidereau R, Byrne JA. Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52 Clin Cancer Res 2008;14:5050-5060
  • Soong R, Shah N, Salto-Tellez M, Tai BC, Soo RA, Han HC, Ng SS, Tan WL, Zeps N, Joseph D, Diasio RB, Iacopetta B. Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy Annals of Oncology 19: 915–919, 2008
  • Tothill RW, Tinker AV, George J, Brown R, Fox SB, Johnson DS, Trivett, MK, Etemadmoghadam D, Locandro B, Traficante N, Fereday S, Hung J, Chiew, Y-E, Haviv I, AOCS Study Group, Gertig, D, deFazio A and Bowtell DDL. Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome. Clin Cancer Res 2008;14:5198-5208
  • Scurr LL, Guminski AD, Chiew YE, Balleine RL, Sharma R, Lei Y, Pryor K, Wain GV, Brand A, Byth K, Kennedy C, Rizos H, Harnett PR, and deFazio, A. Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer Clin Cancer Res 2008;14:6924-6932
  • Anglesio, M., Arnold, J., George, J., Tinker, A., Tothill, R., Waddell, N., Simms, L., Locandro, B., Fereday, S., Traficante, N., Russell, P., Sharma, R., Birrer, M., Australian Ovarian Cancer Study Group, deFazio, A., Chenevix-Trench, G., and Bowtell, D. Mutation of ERBB2 Provides a Novel Alternative Mechanism for the Ubiquitous Activation of RAS-MAPK in Ovarian Serous Low Malignant Potential Tumors Mol Cancer Res 2008;6:1678-1690
  • Gomes, L., Mackie, N., Catchpoole, D., Henwood, T. Test and Teach – In a fix about immunohistochemistry on 60 year old tissue blocks?. Journal of Histotechnology. 2008; 8:125.

 

Research published in 2007 using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Zeps, N. Iacopetta, B.J. Schofield, L. George, J.M. & Goldblatt, J. (2007) ‘Waiver of individual consent in research: When do potential benefits to the community outweigh private rights?’, Medical Journal of Australia 186(2): 88-90
  • Craig C. Whiteford, Sven Bilke, Braden T. Greer, Qingrong Chen, Till A. Braunschweig, Nicola Cenacchi, Jun S. Wei, Malcom A. Smith, Peter Houghton, Christopher Morton, C. Patrick Reynolds, Richard Lock, Richard Gorlick, Chand Khanna, Carol J. Thiele, Mikiko Takikita, Daniel Catchpoole, Stephen M. Hewitt and Javed Khan. “Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis”. Cancer Research 2007;67 (1). January, 2007
  • Greenman C, Stephens P, Smith R, Dalgliesh G, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O’Meara S, Vastrik I, Schmidt E, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew Y-E, deFazio A, Greaves MF, Green AR, Birney E, Easton DF, Chenevix-Trench G, Khoo SK, Tan M-H, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR. Patterns of somatic mutation in human cancer genomes. Nature 446:153-158, 2007
  • Creaney J, van Bruggen I, Hof M, Segal A, Musk AW, de Klerk N, Horick N, Skates SJ, Robinson BW. Combined CA125 and Mesothelin Levels for the Diagnosis of Malignant Mesothelioma. Chest 2007; 132(4): 1239-1246
  • Creaney J, Yeoman D, Naumoff LK, Hof M, Segal A, Musk AW, De Klerk N, Horick N, Skates SJ & Robinson BWS. Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma. Thorax 2007; 62(7): 569-576
  • Catchpoole D.R., Lail A., Guo D., Chen Q., Khan J. Gene expression profiles that segregate patients with childhood acute lymphoblastic leukaemia: An independent validation study identifies that endoglin associates with patient outcome. Leukaemia Research 2007; 31(12): 1741-1747

 

Research published in 2006 using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Stallings R.L., Nair P., Maris J.M., Catchpoole D.R., McDermott M., Breatnach F. and O’Meara A. High resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma. Cancer Research, 66(7), 3673-3680, 2006.
  • Barbaric D, Byth K, Dalla-Pozza L, Byrne JA (2006). Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: Clinical and sample considerations Leukemia Research Volume 30, Issue 11, Pages 1355-1363
  • Han Qian Feng, Anne-Marie Shearwood, Zhao Wen Ying, Nik Zeps, David Joseph, Barry Iacopetta, Arun Dharmarajan sFRP-4 and beta-catenin in Colorectal Carcinoma. Cancer Letters 231 (2006) 129-137
  • Powell A, Creaney J, Broomfield S, Van Bruggen I, Robinson B. Recombinant GM-CSF plus autologous tumor cells as a vaccine for patients with mesothelioma Lung Cancer Volume 52, Issue 2 , Pages 189-197
  • Holloway AJ, Diyagama DS, Opeskin K, Creaney J, Robinson BW, Lake RA, Bowtell DD. A molecular diagnostic test for distinguishing lung adenocarcinoma from malignant mesothelioma using cells collected from pleural effusions. Clin Cancer Res 2006;12:5129-5135
  • Creaney J, Christansen H, Lake R, Musk AB, de Klerk N, Robinson BW. Soluble mesothelin related protein in mesothelioma J Thorac Oncol. 2006;1: 172–174

 

Research published in 2005 using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Astuti D., Latif F., Wagner K., Gentle D., Cooper W.N., Catchpoole D.R., Grundy R., Ferguson-Smith A.C. and Maher E. (2005) Epigenetic alteration at the DLK-GTL2 imprinted domain in human neoplasia provides evidence for trans interaction between DLK1 and GTL2. British Journal of Cancer 92, 1574-1580
  • Gorringe, KL., Boussioutas, A., The Melbourne Gastric Cancer Group, Peter Mac Microarray Facility, Bowtell, DDL. (2005) Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization Genes, Chromosomes and Cancer 42(3): 247-259
  • Henson J.D., et al. (2005) A robust assay for alternative lengthening of telomeres in tumours shows the significance if alternative lengthening of telomeres in sarcomas and astrocytomas Clinical Cancer Research 11, 217-225
  • Sven Bilke, Qing-Rong Chen, Frank Westerman, Manfred Schwab, Daniel Catchpoole, Javed Khan Inferring a Tumour Progression Model for Neuroblastoma from Genomic dataJournal of Clinical Oncology 23(29),2005
  • Margetts C.D.E., Astuti D., Gentle D.C., Cooper W.N., Cascon A., Catchpoole D.R., Robledo M., Neumann H.P.H., Latif F. and Maher E.R. (2005) Epigenetic analysis of HIC1, CASP8, FLIP, TSP1, DcR1, DcR2, DR4, DR5, KvDMR1, H19 and preferential 11p15.5 maternal allele loss in VHL and sporadic phaeochromocytomas Endocrine-Related Cancer 12, 161-172
  • Aghmesheh, M., Edwards, L., Clarke, C.L., Byth, K., Katzenellenbogen, B.S., Russell, P.J., Friedlander, M., Tucker, K.M. and deFazio, A.(2005) Expression of steroid hormone receptors in BRCA1 -associated ovarian carcinomas Gynecologic Oncology 97: 16-25
  • Robinson BWS, Creaney J, Lake R, Nowak A, Musk AW, de Klerk N, Winzell P, Hellstrom KE, Hellstrom I. (2005) Soluble mesothelin-related protein – A blood test for mesothelioma Lung Cancer 49,S1:S109-S111.
  • Mitchell, G., Antill, Y.C., Murray, W., Kirk, J., Salisbury, E., Lindeman, G.J., Di Iulio, J., Milner, A.D., Devereaux, L., Phillips, K. (2005) Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mutation Breast Cancer Research 7:R1122-R1131
  • Creaney J, Robinson BWS. (2005) Detection of mesothelioma in asbestos exposed individuals: The potential role of soluble mesothelin related protein Hematol Oncol Clin North Am. Dec;19(6):1025-40
  • Morgan T., Atkins G.J., Trivett, M.K., Johnson, S.A., Kansara, M., Schlicht, S., Slavin, J.L., Simmons, P., Dickinson, I., Powell, G.J., Choong, P.F.M., and Thomas, D.M. (2005) Molecular Profiling of Giant Cell Tumor of Bone and the Osteoclastic Localization of Ligand for Receptor Activator of Nuclear Factor κB American Journal of Pathology 167(1): 117-28.

 

Research published in 2004 and earlier using tissue specimens supplied by ABN-Oncology-affiliated tissue banks

  • Boussioutas, A., Li, H., Liu, J., Waring, P., Lade, S., Holloway, AJ., Taupin, D., Gorringe, K., Haviv, I., Desmond, P.V., and Bowtell, DDL. (2003) Distinctive Patterns of Gene Expression in Premalignant Gastric Mucosa and Gastric Cancer Cancer Research 63(10): 2569-2577
  • Robinson BW, Creaney J, Lake R, Nowak A, Musk AW, de Klerk N, Winzell P, Hellstrom KE, Hellstrom I. (2003) Mesothelin-family proteins and diagnosis of mesothelioma. The Lancet 362(9396):1612-6
  • Chen Q-R., Bilke S., Wei J.S., Whiteford C.C., Cenacchi N., Krasnoselsky A.L., Greer B., Son C-G., Westermann F., Berthold F., Schwab M., Catchpoole D.R., and Khan J. (2004) cDNA Array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma. BMC Genomics, 5, 70
  • Thomas, D.M., Johnson, S.A., Sims, N.A., Trivett, M., Slavin, J.S., Waring, P. Rubin, B.P., McArthur, G., Walkley, C., Grim, J.E., Clurman, B., Holloway, A., Diyagama, D., Bowtell, D.D.L., Lee, J-S., Gutierrez, G., Piscopo, D.M., Carty, S.A., Hinds, P.W. (2004) Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. Journal of Cell Biology 167: 925-34.
  • Wei J.S., Greer B.T., Steinberg S., Son C-G., Chen Q-R., Westermann F., Whiteford C.C., Bilke S., Cenacchi N., Catchpoole D.R., Berthold F., Schwab M. and Khan J. (2004) Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma. Cancer Research 64(19), 6883-6891
  • Chai M, Zeps N, Joseph D, Goldblatt J, Harvey J, Charles A, Iacopetta B (2004) Screening for defective DNA mismatch repair in stage II and III colorectal cancer patients. Clinical Gastroenterology and Hepatology 2(11):1017-25
  • Robinson BWS. Soluble mesothelin-related protein – a sensitive new marker for mesothelioma. Am J Oncol Rev. 2004;3:230-233